Translational regulation of a novel testis-specific RNF4 transcript.

  title={Translational regulation of a novel testis-specific RNF4 transcript.},
  author={Raffaela Pero and Francesca Lembo and Paolo Chieffi and Giovanna Del Pozzo and Monica Fedele and Alfredo Fusco and Carmelo Bruno Bruni and Lorenzo Chiariotti},
  journal={Molecular reproduction and development},
  volume={66 1},
The RING-finger protein SNURF/RNF4, a modulator of both steroid receptor dependent and basal transcription, is expressed at very high levels in testis and at much lower levels in several other tissues. In somatic tissues, the RNF4 gene is expressed as a 3-kb transcript while an additional shorter sized transcript (1.6 kb) was found in mouse testis. In murine germ cells, RNF4 protein expression is strongly modulated during progression of spermatogonia to spermatids, with a peak in spermatocytes… CONTINUE READING

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