Translational regulation in development

@article{Curtis1995TranslationalRI,
  title={Translational regulation in development},
  author={Daniel F. Curtis and Ruth Lehmann and Phillip D. Zamore},
  journal={Cell},
  year={1995},
  volume={81},
  pages={171-178}
}
Controlling gene expression by regulating translation allows a cell to respond to environmental cues more quickly than de novo transcription permits. Translation of mRNAs transcribed during early oogenesis has long been known to be repressed to permit accumulation of mRNAs for use later in development. In addition to providing such a stockpile of mRNAs, translational regulation has recently been shown to be essential for the generation of protein gradients and the determination of cell fate… CONTINUE READING
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