Translational potential of astrocytes in brain disorders

  title={Translational potential of astrocytes in brain disorders},
  author={Alexei Verkhratsky and L Steardo and Vladimir Parpura and Vedrana Montana},
  journal={Progress in Neurobiology},
Fundamentally, all brain disorders can be broadly defined as the homeostatic failure of this organ. As the brain is composed of many different cells types, including but not limited to neurons and glia, it is only logical that all the cell types/constituents could play a role in health and disease. Yet, for a long time the sole conceptualization of brain pathology was focused on the well-being of neurons. Here, we challenge this neuron-centric view and present neuroglia as a key element in… CONTINUE READING


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