Translational discrimination of mRNAs coding for human insulin-like growth factor II.

@article{Nielsen1990TranslationalDO,
  title={Translational discrimination of mRNAs coding for human insulin-like growth factor II.},
  author={Finn Cilius Nielsen and Steen Gammeltoft and Jan Christiansen},
  journal={The Journal of biological chemistry},
  year={1990},
  volume={265 23},
  pages={13431-4}
}
Sucrose gradient and Northern analyses were used to study the translational status of endogenous multiple mRNAs encoding the prepropeptide for human insulin-like growth factor II. The results showed that a minor 4.8-kilobase mRNA was exclusively engaged in the synthesis of the prepropeptide on membrane-bound polysomes, whereas a major 6.0-kilobase mRNA was present in a cytoplasmic particle which was stable in EDTA. We conclude that the translational discrimination between the mRNAs is dictated… CONTINUE READING

From This Paper

Figures, tables, results, connections, and topics extracted from this paper.
11 Extracted Citations
0 Extracted References
Similar Papers

Citing Papers

Publications influenced by this paper.
Showing 1-10 of 11 extracted citations

Similar Papers

Loading similar papers…