Translational control of InsP3-induced chromatin condensation during the early cell cycles of sea urchin embryos

@article{Twigg1988TranslationalCO,
  title={Translational control of InsP3-induced chromatin condensation during the early cell cycles of sea urchin embryos},
  author={Jeremy P Twigg and Rajnikant Patel and Michael Whitaker},
  journal={Nature},
  year={1988},
  volume={332},
  pages={366-369}
}
The cycles of DNA synthesis and chromatin condensation in dividing cells are controlled by signals from the cytoplasm1–3. Changes in the concentration of free calcium (Cai) in the cytoplasm control a variety of cellular functions4 and it has thus been suggested that observed variations in Cai during the cell cycle may be the cytoplas-mic signal that co-ordinates nuclear and cytoplasmic division5–9. We show here that increases in Cai induced by the calcium-releasing second messenger inositol 1,4… CONTINUE READING