Translational control at the synapse: role of RNA regulators.

@article{Iacoangeli2013TranslationalCA,
  title={Translational control at the synapse: role of RNA regulators.},
  author={Anna Iacoangeli and Henri Tiedge},
  journal={Trends in biochemical sciences},
  year={2013},
  volume={38 1},
  pages={47-55}
}
Translational control of gene expression is instrumental in the regulation of eukaryotic cellular form and function. Neurons in particular rely on this form of control because their numerous synaptic connections need to be independently modulated in an input-specific manner. Brain cytoplasmic (BC) RNAs implement translational control at neuronal synapses. BC RNAs regulate protein synthesis by interacting with eIF4 translation initiation factors. Recent evidence suggests that such regulation is… CONTINUE READING

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