Translational PET imaging research

@article{Hargreaves2014TranslationalPI,
  title={Translational PET imaging research},
  author={Richard J. Hargreaves and Eugenii A. Rabiner},
  journal={Neurobiology of Disease},
  year={2014},
  volume={61},
  pages={32-38}
}
The goal of any early central nervous system (CNS) drug development program is always to test the mechanism and not the molecule in order to support additional research investments in late phase clinical trials. Confirmation that drugs reach their targets using translational positron emission tomography (PET) imaging markers of engagement is central to successful clinical proof-of-concept testing and has become an important feature of most neuropsychiatric drug development programs. CNS PET… CONTINUE READING

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