Translational Genomics: Practical Applications of the Genomic Revolution in Breast Cancer.

@article{Yates2017TranslationalGP,
  title={Translational Genomics: Practical Applications of the Genomic Revolution in Breast Cancer.},
  author={Lucy R. Yates and Christine Desmedt},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2017},
  volume={23 11},
  pages={2630-2639}
}
The genomic revolution has fundamentally changed our perception of breast cancer. It is now apparent from DNA-based massively parallel sequencing data that at the genomic level, every breast cancer is unique and shaped by the mutational processes to which it was exposed during its lifetime. More than 90 breast cancer driver genes have been identified as recurrently mutated, and many occur at low frequency across the breast cancer population. Certain cancer genes are associated with… CONTINUE READING
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