Translation of the mRNA of the maize transcriptional activator Opaque-2 is inhibited by upstream open reading frames present in the leader sequence.

@article{Lohmer1993TranslationOT,
  title={Translation of the mRNA of the maize transcriptional activator Opaque-2 is inhibited by upstream open reading frames present in the leader sequence.},
  author={Stephan Lohmer and Massimo Maddaloni and Mario Motto and Francesco Salamini and Richard D. Thompson},
  journal={The Plant cell},
  year={1993},
  volume={5 1},
  pages={65-73}
}
The protein encoded by the Opaque-2 (O2) gene is a transcription factor, translated from an mRNA that possesses an unusually long 5' leader sequence containing three upstream open reading frames (uORFs). The efficiency of translation of O2 mRNA has been tested in vivo by a transient assay in which the level of activation of the b32 promoter, a natural target of O2 protein, is measured. We show that uORF-less O2 alleles possess a higher transactivation value than the wild-type allele and that… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 49 extracted citations

High rates of polymorphism and recombination at the Opaque-2 locus in cultivated maize

Molecular and General Genetics MGG • 1997
View 5 Excerpts
Highly Influenced

Ribosome profiling reveals dynamic translational landscape in maize seedlings under drought stress.

The Plant journal : for cell and molecular biology • 2015
View 3 Excerpts

Ribosomes and translation in plant developmental control.

Plant science : an international journal of experimental plant biology • 2012
View 2 Excerpts

Similar Papers

Loading similar papers…