Translation of genomic epidemiology of infectious pathogens: Enhancing African genomics hubs for outbreaks

@article{Oboh2020TranslationOG,
  title={Translation of genomic epidemiology of infectious pathogens: Enhancing African genomics hubs for outbreaks},
  author={M. A. Oboh and S. Omoleke and O. Ajibola and J. Manneh and A. Kanteh and A. Sesay and A. Amambua-Ngwa},
  journal={International Journal of Infectious Diseases},
  year={2020},
  volume={99},
  pages={449 - 451}
}
Abstract Background Deadly emerging infectious pathogens place unprecedented challenge on health systems and economies, especially across Africa where health care infrastructures are weak, and poverty rates remain high. Genomic technologies have been vital in enhancing the understanding and development of intervention approaches against these, such as Ebola, and recently the novel coronavirus disease 2019 (COVID-19… Expand
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References

SHOWING 1-10 OF 25 REFERENCES
Real-time, portable genome sequencing for Ebola surveillance
TLDR
This paper presents sequence data and analysis of 142 EBOV samples collected during the period March to October 2015 and shows that real-time genomic surveillance is possible in resource-limited settings and can be established rapidly to monitor outbreaks. Expand
Rapid outbreak sequencing of Ebola virus in Sierra Leone identifies transmission chains linked to sporadic cases
TLDR
It is shown that linked genomic and epidemiological data can not only support contact tracing but also identify unconventional transmission chains involving body fluids, including semen, as part of public health epidemic control efforts. Expand
Preparedness and vulnerability of African countries against importations of COVID-19: a modelling study
TLDR
The preparedness and vulnerability of African countries against their risk of importation of COVID-19 is evaluated, finding that countries with the highest importation risk have moderate to high capacity to respond to outbreaks and countries at moderate risk have variable capacity and high vulnerability. Expand
Genomic characterisation and epidemiology of 2019 novel coronavirus: implications for virus origins and receptor binding
TLDR
The phylogenetic analysis suggests that bats might be the original host of this virus, an animal sold at the seafood market in Wuhan might represent an intermediate host facilitating the emergence of the virus in humans. Expand
Nanopore Sequencing as a Rapidly Deployable Ebola Outbreak Tool
TLDR
A novel, pocket-sized nanopore sequencer is used at a field diagnostic laboratory in Liberia during the current Ebola virus outbreak to perform rapid sequencing of RNA/DNA from pathogen samples obtained during disease outbreaks. Expand
A Novel Coronavirus from Patients with Pneumonia in China, 2019
TLDR
Human airway epithelial cells were used to isolate a novel coronavirus, named 2019-nCoV, which formed a clade within the subgenus sarbecovirus, Orthocoronavirinae subfamily, which is the seventh member of the family of coronaviruses that infect humans. Expand
Quagmire of epidemic disease outbreaks reporting in Nigeria
TLDR
This commentary, based on evidence in the literature and insight from professional experience in the professional experience, concludes that outbreaks are typically regarded as newsworthy events, monitored and reported by both national and international media. Expand
The cost and cost trajectory of whole‐genome analysis guiding treatment of patients with advanced cancers
TLDR
The costs of applying whole‐genome analysis to guide treatments for patients with advanced cancers are estimated and how costs evolve over time is characterized. Expand
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