Translation initiation: variations in the mechanism can be anticipated

@article{Malys2010TranslationIV,
  title={Translation initiation: variations in the mechanism can be anticipated},
  author={Naglis Malys and J. McCarthy},
  journal={Cellular and Molecular Life Sciences},
  year={2010},
  volume={68},
  pages={991-1003}
}
  • Naglis Malys, J. McCarthy
  • Published 2010
  • Medicine, Biology
  • Cellular and Molecular Life Sciences
  • Translation initiation is a critical step in protein synthesis. Previously, two major mechanisms of initiation were considered as essential: prokaryotic, based on SD interaction; and eukaryotic, requiring cap structure and ribosomal scanning. Although discovered decades ago, cap-independent translation has recently been acknowledged as a widely spread mechanism in viruses, which may take place in some cellular mRNA translations. Moreover, it has become evident that translation can be initiated… CONTINUE READING

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