Translating tissue-engineered tracheal replacement from bench to bedside

  title={Translating tissue-engineered tracheal replacement from bench to bedside},
  author={Madhuri Kalathur and Silvia Baiguera and Paolo Macchiarini},
  journal={Cellular and Molecular Life Sciences},
There are a variety of airway diseases with different clinical settings, which may extend from a surgical approach to total organ replacement. Tissue engineering involves modifying cells or tissues in order to repair, regenerate, or replace tissue in the body and seems to be a promising approach for airway replacement. The successful implantation of stem-cell-based tissue-engineered trachea in a young woman with end-stage post-tuberculosis left main bronchus collapse serves as a prototype for… CONTINUE READING
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