Transitions in the transcriptome of the serotonergic and dopaminergic systems in the human brain during adolescence

  title={Transitions in the transcriptome of the serotonergic and dopaminergic systems in the human brain during adolescence},
  author={G. Shoval and Ossnat Bar-Shira and G. Zalsman and J. Mann and Gal Chechik},
  journal={European Neuropsychopharmacology},
  • G. Shoval, Ossnat Bar-Shira, +2 authors Gal Chechik
  • Published 2014
  • Medicine, Biology
  • European Neuropsychopharmacology
  • Adolescence is a period of profound neurophysiological, behavioral, cognitive and psychological changes, but not much is known about the underlying molecular neural mechanisms. The aim of this study was to systematically analyze expression levels of the genes forming serotonergic and dopaminergic synapses during adolescence. We analyzed the mRNA expression profiles of genes that code for all components of serotonergic and dopaminergic synapses, in 16 brain areas from human and non-human… CONTINUE READING


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