Transitional pre-B-cell acute lymphoblastic leukemia of childhood is associated with favorable prognostic clinical features and an excellent outcome: a Pediatric Oncology Group study.

@article{Koehler1993TransitionalPA,
  title={Transitional pre-B-cell acute lymphoblastic leukemia of childhood is associated with favorable prognostic clinical features and an excellent outcome: a Pediatric Oncology Group study.},
  author={Markus Koehler and Frederick G. Behm and Jonathan J Shuster and William M. Crist and Michael J. Borowitz and A Thomas Look and David R. Head and Andrew J. Carroll and Vita J. Land and P C Steuber},
  journal={Leukemia},
  year={1993},
  volume={7 12},
  pages={2064-8}
}
The presenting characteristics and survival of children with the newly recognized transitional cell pre-B immunophenotype of acute lymphoblastic leukemia (ALL) are compared with those of children with pre-B ALL to determine the clinical significance of the new phenotype. Patients with transitional pre-B ALL (n = 17), defined by lymphoblasts expressing cytoplasmic and surface mu heavy chains without kappa or lambda light chains, have lower initial leukocyte counts (p = 0.02) and a higher… CONTINUE READING