Transitional cell carcinoma of the bladder in young adults.
@article{Kutarski1993TransitionalCC,
title={Transitional cell carcinoma of the bladder in young adults.},
author={P W Kutarski and A Padwell},
journal={British journal of urology},
year={1993},
volume={72 5 Pt 2},
pages={
749-55
}
}A retrospective survey of young servicemen presenting with transitional cell carcinoma of the bladder aged 40 years or below is presented, 19 such patients having been identified over a 20-year period. The results were compared with those of other similar series. The tumour behaviour appears to vary with age at presentation, its propensity for multifocal presentation, recurrence, progression to invasion and mortality all rising over the first 4 decades of life. These trends appear to be linked…
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Carcinoma of the bladder in patients under 25 years of age.
- MedicineScandinavian journal of urology and nephrology
- 1996
This study supports the contention that transitional cell carcinoma of the bladder is a less aggressive disease in patients under 25 years of age.
Transitional cell carcinoma of the bladder in young adults: presentation, natural history and outcome.
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Prognosis of Transitional Cell Carcinoma of the Bladder in Patients 40 Years Old or Less: Comparison with Elderly Patients
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TCC of the bladder in patients 40 years old or less has a similar clinicopathological distribution and disease outcome to those observed in elderly patients, and it is suggested that the management and follow-up of TCC ofThe bladder in young patients should be the same.
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Preliminary results of a study using fluorescent in situ hybridization with probes for the centromere of chromosomes 7 and 17 showed a high incidence of aneusomy with regard to these chromosomes and a genetic difference between superficial tumors in the young and in adults.
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The natural history of superficial bladder tumours appears to differ according to age, before the age of 30 years, tumours are frequently stage Ta, well differentiated, with a low recurrence rate, and between the ages of 30 and 40 years, the course of superficial tumours is similar to that observed in older subjects.
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Bladder TCC under 40 years of age usually presents as TaG1, but survival rates are high if follow-up and treatment protocols are followed and there may be bladder tumors in young adult patients regardless of age.
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Bladder urothelial carcinoma in patients younger than 40 years is usually low stage and low grade and management of these patients should be according to clinical characteristics and no different from older patients with the same disease.
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