Transition Metal-Free Visible Light-Driven Photoredox Oxidative Annulation of Arylamidines.


A fast catalytic synthesis of multisubstituted quinazolines from readily available amidines via visible light-mediated oxidative C(sp(3))-C(sp(2)) bond formation has been established. This reaction is a metal-free oxidative coupling catalyzed by a photoredox organocatalyst. The protocol features low catalyst loading (1 mol %). 
DOI: 10.1021/acs.joc.5b02366


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