Transition Metal Free Synthesis of Heterobiaryls Through 1,2-Migration of Boronate Complex.

  title={Transition Metal Free Synthesis of Heterobiaryls Through 1,2-Migration of Boronate Complex.},
  author={Swagata Paul and Kanak Kanti Das and Samir Manna and Santanu Panda},
The synthesis of a diverse range of heterobiaryl has been achieved via a transition metal free sp 2 -sp 2 cross coupling strategy using lithiated heterocycle, aryl or heteroaryl boronic ester and an electrophilic halogen source. The construction of heterobiaryls was carried out through electrophilic activation of the aryl-heteroaryl boronate complex which triggered 1,2-migration from boron to the carbon atom. Subsequent oxidation of the intermediate boronic ester afforded heterobiaryls in good… 
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  • S. Panda, J. Ready
  • Chemistry, Biology
    Journal of the American Chemical Society
  • 2018
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