Transient suppression of gap junctional intercellular communication after exposure to 100-nanosecond pulsed electric fields.

@article{Steuer2016TransientSO,
  title={Transient suppression of gap junctional intercellular communication after exposure to 100-nanosecond pulsed electric fields.},
  author={Anna Steuer and Anke Schmidt and Petra Laboh{\'a} and Pavel Babica and Juergen F. Kolb},
  journal={Bioelectrochemistry},
  year={2016},
  volume={112},
  pages={33-46}
}
Gap junctional intercellular communication (GJIC) is an important mechanism that is involved and affected in many diseases and injuries. So far, the effect of nanosecond pulsed electric fields (nsPEFs) on the communication between cells was not investigated. An in vitro approach is presented with rat liver epithelial WB-F344 cells grown and exposed in a monolayer. In order to observe sub-lethal effects, cells were exposed to pulsed electric fields with a duration of 100ns and amplitudes between… CONTINUE READING