Transient rise in serum soluble Fas (APO-1/CD95) in patients undergoing cardiac surgery.

@article{Kawahito2000TransientRI,
  title={Transient rise in serum soluble Fas (APO-1/CD95) in patients undergoing cardiac surgery.},
  author={Koji Kawahito and Yoshio Misawa and Katsuo Fuse},
  journal={Artificial organs},
  year={2000},
  volume={24 8},
  pages={628-31}
}
The Fas molecule, also designated APO-1/CD95, belongs to the tumor necrosis factor (TNF) receptor family. It is a widely expressed membrane-anchored protein that induces apoptosis by Fas/Fas ligand (Fas-L) mediation. It was reported that Fas-mediated apoptosis plays an important role in regulation of the immune system, systemic inflammatory response, and ischemia/reperfusion injury. A soluble form of Fas (sFas) is produced either through the proteolytic cleavage of membrane-bound receptors or… CONTINUE READING