Transient reduction of PTI-1 expression by short interfering RNAs inhibits the growth of human prostate cancer cell lines.

@article{Yu2006TransientRO,
  title={Transient reduction of PTI-1 expression by short interfering RNAs inhibits the growth of human prostate cancer cell lines.},
  author={Lei Yu and Guojun Wu and Liguo Wang and He Wang and Geng Zhang},
  journal={The Tohoku journal of experimental medicine},
  year={2006},
  volume={209 2},
  pages={
          141-8
        }
}
The prostate tumor-inducing gene 1 (PTI-1) was originally identified by differential ribonucleic acid (RNA) display in human prostate carcinoma. PTI-1 is expressed in human prostate carcinoma but not in benign prostate hypertrophy or normal prostate tissue. PTI-1 may be a member of oncogenes that could affect protein translation and contribute to carcinoma development in human prostate. To investigate the role of PTI-1 in human prostate carcinoma, we constructed three different short… CONTINUE READING

References

Publications referenced by this paper.
SHOWING 1-10 OF 11 REFERENCES

Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1995
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

The prostate: development and physiology.

  • Radiologic clinics of North America
  • 2000
VIEW 2 EXCERPTS

Antisense inhibition of the PTI-1 oncogene reverses cancer phenotypes.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1998
VIEW 1 EXCERPT

Fluorescence in situ hybridization analysis of 8p allelic loss and chromosome 8 instability in human prostate cancer

J. A. Macoska, T. M. Trybus
  • Cancer
  • 1994
VIEW 1 EXCERPT

Prostate cancer progression. Implications of histopathology.

  • The American journal of pathology
  • 1994
VIEW 1 EXCERPT

Deletion mapping of chromosome 8, chromosome 10, and chromosome 16 in human prostatic carcinoma

U. S. Bergerheim, K. Kunimi, V. P. Collins
  • Genes Chromosom Cancer,
  • 1991
VIEW 1 EXCERPT

Potent and specific genetic interference by doublestranded RNA in Caenorbabditis elegans

A. Fire, S. Xu, M. K. Montgomery, S. A. Kostas
  • Nature
  • 1988
VIEW 1 EXCERPT