Transient receptor potential vanilloid 1 expression and function in splenic dendritic cells: a potential role in immune homeostasis.

@article{Assas2016TransientRP,
  title={Transient receptor potential vanilloid 1 expression and function in splenic dendritic cells: a potential role in immune homeostasis.},
  author={Bakri M. Assas and Majed Hamdi Wakid and Haytham Ahmed Zakai and Jaleel Ahmad Miyan and Joanne L Pennock},
  journal={Immunology},
  year={2016},
  volume={147 3},
  pages={292-304}
}
Neuro-immune interactions, particularly those driven by neuropeptides, are increasingly implicated in immune responses. For instance, triggering calcium-channel transient receptor potential vanilloid 1 (TRPV1) on sensory nerves induces the release of calcitonin-gene-related peptide (CGRP), a neuropeptide known to moderate dendritic cell activation and T helper cell type 1 polarization. Despite observations that CGRP is not confined to the nervous system, few studies have addressed the… CONTINUE READING
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