Transient receptor potential channels as therapeutic targets

@article{Moran2011TransientRP,
  title={Transient receptor potential channels as therapeutic targets},
  author={Magdalene M Moran and Michael Allen McAlexander and Tam{\'a}s B{\'i}r{\'o} and Arpad Szallasi},
  journal={Nature Reviews Drug Discovery},
  year={2011},
  volume={10},
  pages={601-620}
}
Transient receptor potential (TRP) cation channels have been among the most aggressively pursued drug targets over the past few years. Although the initial focus of research was on TRP channels that are expressed by nociceptors, there has been an upsurge in the amount of research that implicates TRP channels in other areas of physiology and pathophysiology, including the skin, bladder and pulmonary systems. In addition, mutations in genes encoding TRP channels are the cause of several inherited… Expand

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