Transient receptor potential channel m4 and m5 in magnocellular cells in rat supraoptic and paraventricular nuclei.

@article{Teruyama2011TransientRP,
  title={Transient receptor potential channel m4 and m5 in magnocellular cells in rat supraoptic and paraventricular nuclei.},
  author={Ryoichi Teruyama and Mayumi Sakuraba and Hidekachi Kurotaki and William E. Armstrong},
  journal={Journal of neuroendocrinology},
  year={2011},
  volume={23 12},
  pages={1204-13}
}
The neurohypophysial hormones, vasopressin (VP) and oxytocin (OT), are synthesised by magnocellular cells in the supraoptic nucleus (SON) and the paraventricular nucleus (PVN) of the hypothalamus. The release of VP into the general circulation from the neurohypophysis increases during hyperosmolality, hypotension and hypovolaemia. VP neurones increase hormone release by increasing their firing rate as a result of adopting a phasic bursting. Depolarising after potentials (DAPs) following a… CONTINUE READING