Transient polyadenylation of a maternal mRNA following fertilization of mouse eggs.

@article{Temeles1997TransientPO,
  title={Transient polyadenylation of a maternal mRNA following fertilization of mouse eggs.},
  author={Gretchen L. Temeles and Richard M Schultz},
  journal={Journal of reproduction and fertility},
  year={1997},
  volume={109 2},
  pages={223-8}
}
The molecular basis for the recruitment of maternal mRNAs after fertilization is poorly understood, since there is little information available regarding the identity of such mRNAs. An assay based on reverse transcriptase and PCR was used to identify a maternal mRNA that undergoes a transient polyadenylation after fertilization; the length of the poly(A) tail increases from 40-80 adenosine (A) residues in the unfertilized egg to approximately 250 3 h after insemination and then decreases to… CONTINUE READING

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