Transient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder

@article{Gamis2012TransientMD,
  title={Transient myeloproliferative disorder in children with Down syndrome: clarity to this enigmatic disorder},
  author={A. Gamis and F. O. Smith},
  journal={British Journal of Haematology},
  year={2012},
  volume={159}
}
  • A. Gamis, F. O. Smith
  • Published 2012
  • Medicine
  • British Journal of Haematology
    • Children with trisomy 21 have a unique predisposition to develop a megakaryoblastic proliferative disease of varying severity during their first 3 months of life. This disorder exists in no other children or adults without the presence of trisomy 21 and only occurs in the fetal or neonatal period of life. Its spontaneous resolution in most cases further delineates it from otherwise indistinguishable neonatal leukaemias. The identification that GATA1 mutations are the leukaemogenic source along… CONTINUE READING
    View on Wiley
    onlinelibrary.wiley.com
    53 Citations
    Highly Influencial Citations
    7
    Background Citations
    23
    Methods Citations
    2
    Results Citations
    1
    53 Citations
    Citation Type

    Citation Type

    Transient Myeloproliferative Disorder in Neonates with Down syndrome: Case Report and Review
    • PDF
    Perinatal Transient Myeloproliferative Disorder in Trisomy 21
    • 2
    Transient Myeloproliferative Disorder: An Update for Neonatal Nurses
    Transient Abnormal Myelopoiesis: A Varied Spectrum of Clinical Presentation
    • 4
    • Highly Influenced
    • PDF
    Presentation of Acute Megakaryoblastic Leukemia Associated with a GATA‐1 Mutation Mimicking the Eruption of Transient Myeloproliferative Disorder
    • 1
    • Highly Influenced
    An Instructive Case of Transient Myeloproliferative Disorder
    Myeloid proliferations associated with Down syndrome
    • A. Cantor
    • Medicine
    • Journal of Hematopathology
    • 2014
    • 9
    • PDF
    Recent advances in the understanding of transient abnormal myelopoiesis in Down syndrome
    • K. Watanabe
    • Medicine
    • Pediatrics international : official journal of the Japan Pediatric Society
    • 2019
    • 12
    Neonatal vesiculopustular eruption in Down syndrome and transient myeloproliferative disorder: A case report and review of the literature
    • 1
    A Novel GATA-1 Mutation in a Neonate with Transient Abnormal Myelopoiesis without Down Syndrome

    References

    SHOWING 1-10 OF 91 REFERENCES
    Natural history of transient myeloproliferative disorder clinically diagnosed in Down syndrome neonates: a report from the Children's Oncology Group Study A2971.
    • 138
    Vesiculopustular eruptions in Down syndrome neonates with myeloproliferative disorders.
    • 39
    • PDF
    Insights into the manifestations, outcomes, and mechanisms of leukemogenesis in Down syndrome.
    • 199
    Transient Myeloproliferative Disorder Causing a Vesiculopustular Eruption in a Phenotypically Normal Neonate
    • 27
    Immunophenotype of a transient myeloproliferative disorder in a newborn with trisomy 21.
    • 19
    Analysis of GATA1 mutations in Down syndrome transient myeloproliferative disorder and myeloid leukemia.
    • 72
    • Highly Influential
    Leukemia and/or myeloproliferative syndrome in neonates with Down syndrome.
    • 128
    Transient leukaemia – a benign form of leukaemia in newborn infants with trisomy 21
    • A. Zipursky
    • Biology, Medicine
    • British journal of haematology
    • 2003
    • 185
    Neonatal leukemoid reaction. An isolated manifestation of mosaic trisomy 21.
    • 54
    Incidence and Treatment of Potentially Lethal Diseases in Transient Leukemia of Down Syndrome: Pediatric Oncology Group Study
    • 110