Transient impairment of recognition memory following ibotenic-acid lesions of the basal forebrain in macaques

@article{Aigner1991TransientIO,
  title={Transient impairment of recognition memory following ibotenic-acid lesions of the basal forebrain in macaques},
  author={Thomas G. Aigner and Susan J. Mitchell and John P. Aggleton and Mahlon R. Delong and Robert G. Struble and Donald L. Price and Gary L. Wenk and Karen D. Pettigrew and Mortimer Mishkin},
  journal={Experimental Brain Research},
  year={1991},
  volume={86},
  pages={18-26}
}
To assess the contributions of the basal forebrain cholinergic nuclei to visual recognition memory in macaques, we compared the effects of lesions of (a) the nucleus basalis of Meynert, (b) the medial septal and diagonal band nuclei, and (c) all nuclei combined on performance of delayed nonmatching-to-sample with trial-unique stimuli. Whereas monkeys with the separate lesions did not differ from each other or from normal control animals, those with combined lesions showed a significant… CONTINUE READING
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