Transient hyperthyroidism of hyperemesis gravidarum

@article{Tan2002TransientHO,
  title={Transient hyperthyroidism of hyperemesis gravidarum},
  author={Jackie Yu-Ling Tan and Keh Chuan Loh and George Seow Heong Yeo and Yam Cheng Chee},
  journal={BJOG: An International Journal of Obstetrics \& Gynaecology},
  year={2002},
  volume={109}
}
  • J. Tan, K. Loh, Y. C. Chee
  • Published 1 June 2002
  • Medicine, Biology
  • BJOG: An International Journal of Obstetrics & Gynaecology
Objective To characterise the clinical, biochemical and thyroid antibody profile in women with transient hyperthyroidism of hyperemesis gravidarum. 

Review on hyperemesis gravidarum.

Hyperemesis Gravidarum is a Syndrome of Metabolic and Endocrine Disturbances: A Case Description

TLDR
The management of one case riddled with multiple metabolic events of hyperemesis gravidarum, a clinical syndrome characterized by excess vomiting, dehydration and weight loss associated high human chorionic gonadotropin levels, is described.

Hyperemesis gravidarum: current concepts and management

TLDR
A general outline of the hyperemesis gravidarum, its relation to the gastrointestinal system and thyroid, mild and rare severe complications, and conventional treatment versus newer options are discussed.

Severe Hyperemesis Gravidarum Masking the Presentations of Hyperthyroidism

TLDR
Goiter and refractory tachycardia are the useful clues to detect occult hyperthyroidism in patients with hyperemesis gravidarum.

Severe Hyperemesis Gravidarum Masking the Presentations of Hyperthyroidism

TLDR
Goiter and refractory tachycardia are the useful clues to detect occult hyperthyroidism in patients with hyperemesis gravidarum.

Thyroid Function and Serum Free BHCG Levels in Hyperemesis Gravidarum

TLDR
This study investigated the relationship between beta human chorionic gonadotrophin (BHCG) and throyid function with HG among pregnant women admitted to Sari Imam Khomeini Hospital.

Thyroid dysfunction in hyperemesis gravidarum: a study in Turkish pregnant women.

  • N. AkdemirC. Bilir
  • Medicine, Biology
    Journal of the Turkish German Gynecological Association
  • 2011
TLDR
Hyperemesis gravidarum can be a risk factor for postpartum thyroid dysfunction and thyroid antibodies must be checked in the hyperemesis population in an endemic goitre region and/or iodine replacement regions.

Hyperthyroidism and Pregnancy.

  • K. KobalyS. Mandel
  • Medicine, Biology
    Endocrinology and metabolism clinics of North America
  • 2019

Thyroid Storm Caused by Hyperemesis Gravidarum

Hyperthyroidism During Pregnancy: A Clinical Approach.

  • Ryan D Cuff
  • Medicine
    Clinical obstetrics and gynecology
  • 2019
TLDR
The clinical management, including the indications for the use of thioamide or antithyroid medications, will be discussed in the context of pregnancy, and considerations for the management of the postpartum and/or breastfeeding patient with hyperthyroidism will be reviewed.
...

References

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Transient hyperthyroidism and hyperemesis gravidarum: clinical aspects.

Increased concentration of the free β‐subunit of human chorionic gonadotropin in hyperemesis gravidarum

TLDR
Sera from singleton gestations with hyperemesis gravidarum contained a higher proportion of free β hCG compared to controls of comparable gestational age, as well as other conditions associated with high total hCG.

Hyperemesis Gravidarum and the Sex of the Offspring

TLDR
Findings provide evidence that pregnant women with a diagnosis of hyperemesis gravidarum in the first trimester give birth to a higher proportion of female newborns than do all mothers, regardless of whether they are hospitalized.

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TLDR
Some degree of stimulation of the thyroid gland by human chorionic gonadotropin is common during early pregnancy, but overt hyperthyroidism may ensue when serum chorionics concentrations are abnormally high.

Severity of hyperemesis gravidarum correlates with serum levels of reverse T3

TLDR
The data are consistent with a shift from T3 to rT3 as products of 5′-monodeiodination of thyroxine in hyperemesis gravidarum, and a control mechanism may be postulated wherein T3 production is minimized, thereby reducing weight loss and lipolysis in patients with hyperemetic women.

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TLDR
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TLDR
The data indicate that the thyroid gland is physiologically activated in early pregnancy, possibly by hCG or a related substance, which may induce gestational emesis and may not necessitate antithyroid drug treatment.