Transient gene delivery for functional enrichment of differentiating embryonic stem cells.


There is a critical need for new sources of hepatocytes, both clinically to provide support for patients with liver failure and in drug discovery for toxicity, metabolic and pharmacokinetic screening of new drug entities. We have reported previously a variety of methods for differentiating murine embryonic stem (ES) cells into hepatocyte-like cells. One… (More)
DOI: 10.1002/bit.22027


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