Transient expression of lysyl oxidase by liver myofibroblasts in murine schistosomiasis.


BACKGROUND Murine schistosomiasis provides an experimental model of reversible fibrosis. The lysyl oxidase catalyzes the first step of collagen and elastin enzymatic cross-linking and appears to be a crucial factor in stabilizing the neosynthesized extracellular matrix in the liver. EXPERIMENTAL DESIGN A cDNA probe encoding a portion of the murine lysyl… (More)


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