Transient expression of Ym1, a heparin-binding lectin, during developmental hematopoiesis and inflammation.

@article{Hung2002TransientEO,
  title={Transient expression of Ym1, a heparin-binding lectin, during developmental hematopoiesis and inflammation.},
  author={Shuen-Iu Hung and Alice Chien Chang and I. Kato and Nan-Chi A Chang},
  journal={Journal of leukocyte biology},
  year={2002},
  volume={72 1},
  pages={72-82}
}
Ym1, a secretory protein transiently produced by activated peritoneal macrophages elicited by parasitic infections, has been identified as a novel heparin-binding lectin. X-ray crystallography study revealed that Ym1 has a beta/alpha barrel structure with a carbohydrate-binding cleft similar to that of triose-phosphate isomerases. To further delineate the physiological significance of Ym1, we examined its expression patterns during mouse embryonic development and inflammation states elicited by… CONTINUE READING
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Anatomy and physiology of hematopoiesis

  • C. M. Verfaillie
  • 2000
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