Transient cortical blindness and bioccipital brain lesions in two patients with acute intermittent porphyria.

@article{Kupferschmidt1995TransientCB,
  title={Transient cortical blindness and bioccipital brain lesions in two patients with acute intermittent porphyria.},
  author={H Kupferschmidt and Antoon F. De Bont and H Schnorf and Theodor Landis and E Walter and J Peter and S Kr{\"a}henb{\"u}hl and P J Meier},
  journal={Annals of internal medicine},
  year={1995},
  volume={123 8},
  pages={598-600}
}
The most common neurologic manifestations of acute intermittent porphyria are autonomic visceral neuropathy, peripheral motor neuropathy, and central nervous system dysfunctions, including seizures and neuropsychiatric disturbances [1]. In rare instances, however, patients with acute intermittent porphyria have presented with acute cortical blindness [2-5], for which deleterious vasospasm in both posterior cerebral arteries has been inferred [3, 6]. We describe two patients in whom cortical… CONTINUE READING
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