Transient binding and dissipation in cross-linked actin networks.

Abstract

In contrast with entangled actin solutions, transiently cross-linked actin networks can provide highly elastic properties while still allowing for local rearrangements in the microstructure-on biological relevant time scales. Here, we show that thermal unbinding of transient cross-links entails local stress relaxation and energy dissipation in an intermediate elasticity dominated frequency regime. We quantify the viscoelastic response of an isotropically cross-linked actin network by experimentally tuning the off rate of the transiently cross-linking molecules, their density, and the solvent viscosity. We reproduce the measured frequency response by a semiphenomenological model that is predicated on microscopic unbinding events.

2 Figures and Tables

01020200920102011201220132014201520162017
Citations per Year

66 Citations

Semantic Scholar estimates that this publication has 66 citations based on the available data.

See our FAQ for additional information.

Cite this paper

@article{Lieleg2008TransientBA, title={Transient binding and dissipation in cross-linked actin networks.}, author={Oliver Lieleg and Mireille M. A. E. Claessens and Yiliang Luan and Andreas R. Bausch}, journal={Physical review letters}, year={2008}, volume={101 10}, pages={108101} }