Transient behavioral sensitization to nicotine becomes long-lasting with monoamine oxidases inhibitors
@article{Villgier2003TransientBS, title={Transient behavioral sensitization to nicotine becomes long-lasting with monoamine oxidases inhibitors}, author={Anne-Sophie Vill{\'e}gier and G{\'e}rard Blanc and Jacques Glowinski and Jean Pol Tassin}, journal={Pharmacology Biochemistry and Behavior}, year={2003}, volume={76}, pages={267-274} }
77 Citations
Inhibition of Monoamine Oxidases Desensitizes 5-HT1A Autoreceptors and Allows Nicotine to Induce a Neurochemical and Behavioral Sensitization
- Biology, ChemistryThe Journal of Neuroscience
- 2009
Data indicate that a repeated treatment with a mixture of nicotine and tranylcypromine induces both behavioral sensitization and sensitization of noradrenergic and serotonergic neurons, and MAOIs contained in tobacco desensitize 5-HT1A autoreceptors to trigger the strong addictive properties of tobacco.
Chronic treatment with monoamine oxidase-B inhibitors decreases cocaine reward in mice
- Biology, PsychologyPsychopharmacology
- 2009
It is suggested that long-term treatments with MAO-B inhibitors may decrease cocaine-supported operant responses in cocaine-naïve mice by selectively decreasing frontal cortical metabolism of dopamine and serotonin.
Irreversible blockade of monoamine oxidases reveals the critical role of 5‐HT transmission in locomotor response induced by nicotine in mice
- Biology, PsychologyThe European journal of neuroscience
- 2006
The data suggest that mixed irreversible MAOIs contained in tobacco facilitate the effects of Nicotine on serotonin release, thus allowing the locomotor and rewarding effects of nicotine.
Monoamine Oxidase Inhibitors Allow Locomotor and Rewarding Responses to Nicotine
- Biology, PsychologyNeuropsychopharmacology
- 2006
The data suggest that MAOIs contained in tobacco and tobacco smoke act in synergy with nicotine to enhance its rewarding effects.
Tranylcypromine enhancement of nicotine self-administration
- Biology, MedicineNeuropharmacology
- 2007
Monoamine Oxidase Inhibition Dramatically Prolongs the Duration of Nicotine Withdrawal-Induced Place Aversion
- Biology, PsychologyBiological Psychiatry
- 2008
Uncoupling between noradrenergic and serotonergic neurons as a molecular basis of stable changes in behavior induced by repeated drugs of abuse.
- Biology, PsychologyBiochemical pharmacology
- 2008
Serotonergic mechanism underlying tranylcypromine enhancement of nicotine self‐administration
- Biology, PsychologySynapse
- 2011
It is suggested that MAO inhibition enhances serotonergic transmission, which serves a critical role in the reinforcing effects of nicotine.
Inhibition of monoamine oxidase isoforms modulates nicotine withdrawal syndrome in the rat.
- Biology, MedicineLife sciences
- 2013
Nicotine produces chronic behavioral sensitization with changes in accumbal neurotransmission and increased sensitivity to re‐exposure
- Biology, PsychologyAddiction biology
- 2016
It is found that nicotine produces persistent neural adaptations that make the system sensitive and receptive to future nicotine re‐exposure 7 months after the initial behavioral sensitization.
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