Transient anomalies in genital appearance in some extremely preterm female infants may be the result of foetal programming causing a surge in LH and the over activation of the pituitary-gonadal axis.

Abstract

AIM Animal studies have linked foetal programming with the development of the polycystic ovarian syndrome, and metabolic syndrome, in adulthood. The objective is to describe the investigation of four extreme-premature female infants born between 25 and 29 weeks' gestation with apparent genital abnormalities in association with unusually high androgens and… (More)
DOI: 10.1111/j.1365-2265.2008.03298.x

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Cite this paper

@article{Greaves2008TransientAI, title={Transient anomalies in genital appearance in some extremely preterm female infants may be the result of foetal programming causing a surge in LH and the over activation of the pituitary-gonadal axis.}, author={Ronda F. Greaves and Rodney W. Hunt and Margaret R. Zacharin}, journal={Clinical endocrinology}, year={2008}, volume={69 5}, pages={763-8} }