Transient and long-lasting effects of iontophoretically administered norepinephrine on somatosensory cortical neurons in halothane-anesthetized cats.

@article{Warren1996TransientAL,
  title={Transient and long-lasting effects of iontophoretically administered norepinephrine on somatosensory cortical neurons in halothane-anesthetized cats.},
  author={Richard A. Warren and Robert W. Dykes},
  journal={Canadian journal of physiology and pharmacology},
  year={1996},
  volume={74 1},
  pages={38-57}
}
We examined the modulatory effects of iontophoretically administered norepinephrine (NE) on the excitability of 117 neurons in cat somatosensory cortex. NE was released in the vicinity of neurons with receptive fields (31/117) while they were excited by somatic stimuli and near neurons without receptive fields (86/117) while they were excited by glutamate. In 54% of the neurons (n = 63) the effects were inhibitory, decreasing both the spontaneous and the driven activity. Most of these cells… CONTINUE READING

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