Transient and controllable opening of the blood-brain barrier to cytostatic and antibiotic agents by alkylglycerols in rats


The blood-brain barrier hinders progress in the chemotherapy of brain tumors due to insufficient penetration of anticancer drugs into the brain tissue. Short-chain alkylglycerols affect the physicochemical properties of biological membranes. The enhancement of the blood-brain barrier permeability by intra-arterial administration of alkylglycerols was… (More)
DOI: 10.1007/s002210000553


5 Figures and Tables

Slides referencing similar topics