Transient Expression of Biologically Active Anti-rabies Virus Monoclonal Antibody in Tobacco Leaves

@inproceedings{Shafaghi2018TransientEO,
  title={Transient Expression of Biologically Active Anti-rabies Virus Monoclonal Antibody in Tobacco Leaves},
  author={Mona Shafaghi and Somayeh Maktoobian and Rahimeh Rasouli and Nader Howaizi and Hamideh Ofoghi and Parastoo Ehsani},
  booktitle={Iranian journal of biotechnology},
  year={2018}
}
Background Rabies virus is a neurotropic virus that causes fatal, but, a preventable disease in mammals. Administration of rabies immunoglobulin (RIG) is essential for the post-exposure of the prophylaxis to prevent the disease. However, replacement of polyclonal RIGs with alternative monoclonal antibodies (MAbs) that are capable of neutralizing rabies virus has been recommended. Objectives Here, we have investigated the transient expression of the full-size human MAb against rabies virus… CONTINUE READING

Similar Papers

References

Publications referenced by this paper.
SHOWING 1-10 OF 59 REFERENCES

Function and glycosylation of plant-derived antiviral monoclonal antibody.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 2003
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

Co - expression of hepatitis C virus polytope – HBsAg and p 19 - silencing suppressor protein in tobacco leaves

Y Sheludko, Y Sindarovska, I Gerasymenko, M Bannikova, N Kuchuk
  • Pharm Biol
  • 2015