Transient Cerebral Ischemia Induces Active Astrocytosis Without Distinct Neuronal Death in the Gerbil Main Olfactory Bulb: A Long-Term Analysis

@article{Choi2010TransientCI,
  title={Transient Cerebral Ischemia Induces Active Astrocytosis Without Distinct Neuronal Death in the Gerbil Main Olfactory Bulb: A Long-Term Analysis},
  author={Jung Hoon Choi and Ki-Yeon Yoo and Choong Hyun Lee and Ok kyu Park and Bing Chun Yan and Hua Li and Yoo Sun Moon and In Koo Hwang and Yun Lyul Lee and Hyung-Cheul Shin and Moo-ho Won},
  journal={Neurochemical Research},
  year={2010},
  volume={35},
  pages={1588-1598}
}
In the present study, we examined ischemia-induced neuronal and glial changes in the gerbil MOB at various time points during 60 days after 5 min of transient cerebral ischemia. The number of neuronal neuclei-immunoreactive neurons was not changed after ischemia/reperfusion (I/R). Myelin basic protein immunoreaction was well preserved after I/R. Five days after I/R, reactive form of GFAP-immunoreactive astrocytes began to increase in the external plexiform layer and granule cell layer: These… CONTINUE READING

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