Corpus ID: 25894885

Transhepatic transport of taurocholic acid in normal and mutant analbuminemic rats.

@article{Inoue1985TranshepaticTO,
  title={Transhepatic transport of taurocholic acid in normal and mutant analbuminemic rats.},
  author={Masayasu Inoue and Yoshimasa Morino and Sumi Nagase},
  journal={Biochimica et biophysica acta},
  year={1985},
  volume={833 2},
  pages={
          211-6
        }
}
  • Masayasu Inoue, Yoshimasa Morino, Sumi Nagase
  • Published in Biochimica et biophysica acta 1985
  • Medicine
  • To elucidate a possible function of plasma albumin in vectorial transport of various cholephilic organic anions, such as bile acids, plasma clearance and transhepatic transport of radioactive taurocholate were studied in vivo in normal and mutant analbuminemic rats. Intravenous administration of taurocholate was followed by its rapid disappearance from the circulation in both animal groups. However, plasma clearance of taurocholate was significantly larger in analbuminemic (68.3 ml/min per kg… CONTINUE READING

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