Transglutaminase activity is decreased in large arteries from hypertensive rats compared with normotensive controls.


Transglutaminases (TGs) catalyze the formation of covalent cross-links between glutamine residues and amine groups. This cross-linking activity has been implicated in arterial remodeling. Because hypertension is characterized by arterial remodeling, we hypothesized that TG activity, expression, and functionality would be increased in the aorta, but not in… (More)
DOI: 10.1152/ajpheart.00402.2014

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