Transgenic silkworms (Bombyx mori) produce recombinant spider dragline silk in cocoons
@article{Wen2009TransgenicS, title={Transgenic silkworms (Bombyx mori) produce recombinant spider dragline silk in cocoons}, author={H. Wen and Xiqian Lan and Yuansong Zhang and Tianfu Zhao and Y. Wang and Zenta Kajiura and M. Nakagaki}, journal={Molecular Biology Reports}, year={2009}, volume={37}, pages={1815-1821} }
Spider dragline silk is a unique fibrous protein with a combination of tensile strength and elasticity, but the isolation of large amounts of silk from spiders is not feasible. In this study, we generated germline-transgenic silkworms (Bombyx mori) that spun cocoons containing recombinant spider silk. A piggyBac-based transformation vector was constructed that carried spider dragline silk (MaSp1) cDNA driven by the sericin 1 promoter. Silkworm eggs were injected with the vector, producing… CONTINUE READING
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