Transgenic porcine valves show no signs of delayed cardiac xenograft rejection.

@article{Chen2001TransgenicPV,
  title={Transgenic porcine valves show no signs of delayed cardiac xenograft rejection.},
  author={Raymond H. Chen and David H Adams},
  journal={The Annals of thoracic surgery},
  year={2001},
  volume={71 5 Suppl},
  pages={
          S389-92
        }
}
BACKGROUND Glutaraldehyde fixation stiffens the structural integrity of porcine valves, although the solution also destroys tissue viability and accelerates calcification. Recently, we demonstrated that fresh cardiac valves from domestic pigs do not express the galactose alpha1, 3 galactose (alpha-Gal) antigen and may be immunologically unique. The absence… CONTINUE READING