Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack

@article{Tavladoraki1993TransgenicPE,
  title={Transgenic plants expressing a functional single-chain Fv antibody are specifically protected from virus attack},
  author={Paraskevi Tavladoraki and Eugenio Benvenuto and Stefania Trinca and Domenico De Martinis and Antonino Cattaneo and Patrizia Galeffi},
  journal={Nature},
  year={1993},
  volume={366},
  pages={469-472}
}
EXPRESSION of viral genes in transgenic plants is a very effective tool for attenuating plant viral infection1–3. Nevertheless, the lack of generality and risk issues related to the expression of viral genes in plants4 might limit the exploitation of this strategy. Expression in plants of antibodies against essential viral proteins could provide an alternative approach to engineer viral resistance. Recently, expression of complete5–7 or engineered7–9 antibodies has been successfully achieved in… CONTINUE READING
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