Transgenic models of HIV-1.

  title={Transgenic models of HIV-1.},
  author={Paul E. Klotman and Jay Rappaport and Pritha Ray and Jeffrey B. Kopp and Roberta R Franks and Leslie A. Bruggeman and Abner Louis Notkins},
  volume={9 4},
Transgenic technology has been very successful at providing insights into possible processes involved in HIV-induced pathogenesis. The availability of these small animal models for the study of HIV-related syndromes including KS, epidermal proliferative lesions, HIV-associated nephropathy, AIDS-related growth failure and cachexia may well facilitate the development of novel therapies for these complications. Other phenotypes created in mice, such as cataracts and hepatic cancer [59], may not… CONTINUE READING


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