Transgenic models for Hepatitis C virus pathogenesis

Abstract

The use of reverse genetics in the mouse, allowing flexible gene manipulation, has been one of the most powerful tools in the last decade for the understanding of complex biological phenomena. Transgenic and knock-out animal models have yet been fruitfully used in the understanding of the molecular basis of several human diseases. ± 3 Notably, the… (More)
DOI: 10.1038/sj.cdd.4401114

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