Transgenic mice with pancellular enhanced green fluorescent protein expression in primitive hematopoietic cells and all blood cell progeny.

@article{Dominici2005TransgenicMW,
  title={Transgenic mice with pancellular enhanced green fluorescent protein expression in primitive hematopoietic cells and all blood cell progeny.},
  author={Massimo Dominici and Merhdad Tadjali and Steven Kepes and Esther R. Allay and Kelli Boyd and Paul A. Ney and Edwin Horwitz and Derek A. Persons},
  journal={Genesis},
  year={2005},
  volume={42 1},
  pages={17-22}
}
Transgenic mice homogeneously expressing enhanced green fluorescence protein (EGFP) in primitive hematopoietic cells and all blood cell progeny, including erythrocytes and platelets, have not been reported. Given previous data indicating H2Kb promoter activity in murine hematopoietic stem cells (HSCs), bone marrow (BM), and lymphocytes, an H2Kb enhancer/promoter EGFP construct was used to generate transgenic mice. These mice demonstrated pancellular EGFP expression in both primitive BM Sca-1… CONTINUE READING

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