Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells.

  title={Transgenic mice with green fluorescent protein-labeled pancreatic beta -cells.},
  author={Manami Hara and Xiaoyu Wang and Toshihiko Kawamura and Vytas P. Bindokas and Restituto F. Dizon and Sergio Y. Alcoser and Mark A Magnuson and Graeme I. Bell},
  journal={American journal of physiology. Endocrinology and metabolism},
  volume={284 1},
We have generated transgenic mice that express green fluorescent protein (GFP) under the control of the mouse insulin I gene promoter (MIP). The MIP-GFP mice develop normally and are indistinguishable from control animals with respect to glucose tolerance and pancreatic insulin content. Histological studies showed that the MIP-GFP mice had normal islet architecture with coexpression of insulin and GFP in the beta-cells of all islets. We observed GFP expression in islets from embryonic day E13.5… CONTINUE READING
Highly Influential
This paper has highly influenced 13 other papers. REVIEW HIGHLY INFLUENTIAL CITATIONS


Publications citing this paper.
Showing 1-10 of 104 extracted citations

Similar Papers

Loading similar papers…