Transgenic mice that express Cre recombinase in hypertrophic chondrocytes.

@article{Yang2005TransgenicMT,
  title={Transgenic mice that express Cre recombinase in hypertrophic chondrocytes.},
  author={Guan Gen Yang and Fang Cui and Ning Hou and Xuan Cheng and Jishuai Zhang and Youliang Wang and Nan Jiang and Xiang Gao and Xiao Yang},
  journal={Genesis},
  year={2005},
  volume={42 1},
  pages={33-6}
}
In order to investigate the physiological control of hypertrophic chondrocytes which present the terminally differentiated form of chondrocytes, we generated a mouse line expressing the Cre recombinase under the control of the mouse type X collagen (Col10a1) promoter. In situ hybridization analysis demonstrated the expression of Col10a1-Cre transgene in hypertrophic chondrocytes of femur at postnatal day 2 (P2). In order to test the excision activity of the Cre recombinase, the Col10a1-Cre… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

Similar Papers

Loading similar papers…