Transgenic mice display hair loss and regrowth overexpressing mutant Hr gene

Abstract

Mutations in the hairless (Hr) gene in both mice and humans have been implicated in the development of congenital atrichia, but the role of Hr in skin and hair follicle (HF) biology remains unknown. Here, we established transgenic mice (TG) overexpressing mutant Hr to investigate its specific role in the development of HF. Three transgenic lines were… (More)
DOI: 10.1538/expanim.16-0115

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