Transgenic expression of matrix metalloproteinase-2 induces coronary artery ectasia.

  title={Transgenic expression of matrix metalloproteinase-2 induces coronary artery ectasia.},
  author={Sia Dahi and Joel S. Karliner and Rajabrata Sarkar and David H. Lovett},
  journal={International journal of experimental pathology},
  volume={92 1},
Coronary artery ectasia (CAE) is generally diagnosed in patients undergoing arteriography for presumptive atherosclerotic coronary artery disease. CAE is commonly considered as a variant of atherosclerotic disease; however, recent studies suggest that CAE is the result of a systemic vascular disorder. There is increasing evidence that aneurysmal vascular disease is a systemic disorder characterized by enhanced expression of pro-inflammatory cytokines and increased synthesis of enzymes capable… CONTINUE READING
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